Biology – Quantitative Biology – Neurons and Cognition
Scientific paper
2006-05-03
Biology
Quantitative Biology
Neurons and Cognition
19 pages, 8 figures
Scientific paper
Using a realistic model of activity dependent dynamical synapses and a standard integrate and fire neuron model we study, both analytically and numerically, the conditions in which a postsynaptic neuron efficiently detects temporal coincidences of spikes arriving at certain frequency from N different afferents. We extend a previous work that only considers synaptic depression as the most important mechanism in the transmission of information through synapses, to a more general situation including also synaptic facilitation. Our study shows that: 1) facilitation enhances the detection of correlated signals arriving from a subset of presynaptic excitatory neurons, with different degrees of correlation among this subset, and 2) the presence of facilitation allows for a better detection of firing rate changes. Finally, we also observed that facilitation determines the existence of an optimal input frequency which allows the best performance for a wide (maximum) range of the neuron firing threshold. This optimal frequency can be controlled by means of facilitation parameters.
Mejias Jorge F.
Torres Joaquin J.
No associations
LandOfFree
The role of synaptic facilitation in coincidence spike detection does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.
If you have personal experience with The role of synaptic facilitation in coincidence spike detection, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and The role of synaptic facilitation in coincidence spike detection will most certainly appreciate the feedback.
Profile ID: LFWR-SCP-O-307584