The Context Sensitivity Problem in Biological Sequence Segmentation

Details The Context Sensitivity Problem in Biological Sequence Segmentation The Context Sensitivity Problem in Biological Sequence Segmentation

2009-04-17

arxiv.org/abs/0904.2668v1

Biology

Quantitative Biology

Genomics

IEEEtran class, 39 pages, 20 figures

Scientific paper

In this paper, we describe the context sensitivity problem encountered in partitioning a heterogeneous biological sequence into statistically homogeneous segments. After showing signatures of the problem in the bacterial genomes of Escherichia coli K-12 MG1655 and Pseudomonas syringae DC3000, when these are segmented using two entropic segmentation schemes, we clarify the contextual origins of these signatures through mean-field analyses of the segmentation schemes. Finally, we explain why we believe all sequence segmentation schems are plagued by the context sensitivity problem.

Affiliated with

Also associated with

No associations

Rating

The Context Sensitivity Problem in Biological Sequence Segmentation does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with The Context Sensitivity Problem in Biological Sequence Segmentation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and The Context Sensitivity Problem in Biological Sequence Segmentation will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-141109