Computer Science – Computational Complexity
Scientific paper
2012-04-10
Computer Science
Computational Complexity
14 pages main text + 13 pages appendix. Full version with proofs of an article appearing in the Proceedings of the 23rd Annual
Scientific paper
Given a string $w$ over a finite alphabet $\Sigma$ and an integer $K$, can $w$ be partitioned into strings of length at most $K$, such that there are no \emph{collisions}? We refer to this question as the \emph{string partition} problem and show it is \NP-complete for various definitions of collision and for a number of interesting restrictions including $|\Sigma|=2$. This establishes the hardness of an important problem in contemporary synthetic biology, namely, oligo design for gene synthesis.
Condon Anne
Manuch Jan
Thachuk Chris
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