Computer Science – Systems and Control
Scientific paper
2012-03-06
Computer Science
Systems and Control
Technical Report accompanying CDC 2012 submission
Scientific paper
Many biological oscillators are arranged in networks composed of many inter-coupled cellular oscillators. However, results are still lacking on the collective oscillation period of inter-coupled gene regulatory oscillators, which, as has been reported, may be different from the oscillation period of an autonomous cellular oscillator. Based on the Goodwin oscillator, we analyze the collective oscillation pattern of coupled cellular oscillator networks. First we give a condition under which the oscillator network exhibits oscillatory and synchronized behavior, then we estimate the collective oscillation period based on a multivariable harmonic balance technique. Analytical results are derived in terms of biochemical parameters, thus giving insight into the basic mechanism of biological oscillation and providing guidance in synthetic biology design. Simulation results are given to confirm the theoretical predictions.
Doyle III Francis J.
Hara Shinji
Hori Yutaka
Wang Yongqiang
No associations
LandOfFree
The collective oscillation period of inter-coupled Goodwin oscillators does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.
If you have personal experience with The collective oscillation period of inter-coupled Goodwin oscillators, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and The collective oscillation period of inter-coupled Goodwin oscillators will most certainly appreciate the feedback.
Profile ID: LFWR-SCP-O-537759