Stratospheric balloon BIRBA 2 mission: effects of cosmic radiations on gene expression of human cells

Details Stratospheric balloon BIRBA 2 mission: effects of cosmic radiations on gene expression of human cells Stratospheric balloon BIRBA 2 mission: effects of cosmic radiations on gene expression of human cells

Aug 2003

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=2003esasp.530..571g&link_type=abstract

In: 16th ESA Symposium on European Rocket and Balloon Programmes and Related Research, 2 - 5 June 2003, Sankt Gallen, Switzerlan

Biology

Space Research: Biology

Scientific paper

In space living organisms, including cells, are affected by two new environmental conditions: microgravity and cosmic radiations. In order to evaluate the effects of cosmoc radiation on the gene expression we exposed human cell lines to high quote cosmic radiation during stratospheric balloon trans-mediterranean flights (BIRBA2, mission 2002). To this purpose HUVEC (endotelial human cells) and purified human T lymphocytes, were used. After a 22 h flight the cells lines were examinated by the cDNA microarrays method, proved to be very sensible and accurate. A panel of genes candidate to be defined modulated by cosmic radiation has been isolated.

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