Spatiotemporal Noise Triggering Infiltrative Tumor Growth under Immune Surveillance

Details Spatiotemporal Noise Triggering Infiltrative Tumor Growth under Immune Surveillance Spatiotemporal Noise Triggering Infiltrative Tumor Growth under Immune Surveillance

2008-01-02

arxiv.org/abs/0801.0357v1

Biology

Quantitative Biology

Other Quantitative Biology

8 pages, 6 figures

Scientific paper

10.1209/0295-5075/82/20003

A spatiotemporal noise is assumed to reflect the environmental fluctuation in a spatially extended tumor system. We introduce firstly the structure factor to reveal the invasive tumor growth quantitatively. The homogenous environment can lead to an expansive growth of the tumor cells, while the inhomogenous environment underlies an infiltrative growth. The different responses of above two cases are separated by a characteristic critical intensity of the spatiotemporal noise. Theoretical and numerical results present a close annotation to the clinical images.

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