Solvent content of protein crystals from diffraction intensities by Independent Component Analysis

Biology – Quantitative Biology – Quantitative Methods

Scientific paper

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9 pages, 2 figures, 1 table

Scientific paper

10.1016/j.physa.2004.11.005

An analysis of the protein content of several crystal forms of proteins has
been performed. We apply a new numerical technique, the Independent Component
Analysis (ICA), to determine the volume fraction of the asymmetric unit
occupied by the protein. This technique requires only the crystallographic data
of structure factors as input.

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