Sex Differences in Renal Toxicity of Mercury in the Rat

Details Sex Differences in Renal Toxicity of Mercury in the Rat Sex Differences in Renal Toxicity of Mercury in the Rat

Mar 1964

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=1964natur.201.1235h&link_type=abstract

Nature, Volume 201, Issue 4925, pp. 1235 (1964).

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A PRONOUNCED sex difference was found to exist in the renal tubules of rats injected intravenously with minimally toxic doses of bichloride of mercury. Mercury, in toxic doses, produces an acute tubular necrosis in a wide variety of experimental animals and man1,2. Histologically, when minimally toxic doses are given to rats, the lesions are confined to the straight portions of the proximal tubules.

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