Semi-Circular Canals Anomalies//Idiopathic Scoliosis

Details Semi-Circular Canals Anomalies//Idiopathic Scoliosis Semi-Circular Canals Anomalies//Idiopathic Scoliosis

2010-03-03

arxiv.org/abs/1003.0836v1

Biology

Quantitative Biology

Neurons and Cognition

15 pages, 8 figures Name and adress for correspondence: Docteur Rousie, 3 rue Saint Louis, 59113 Seclin France. Fax: 0033 320

Scientific paper

Thanks to a novel modelling programme to detect anomalies in the membranous semi circular canals (SSC) of idiopathic scoliosis (IS) we found severe anomalies mainly located in lateral SCC devoted to trunk rotation and lateral deviations. We also found a specific communication between the lateral and posterior canal involving the utricular chamber which is also highly suspected in scoliosis. Key points: - Membranous semi circular canals (SCC) modelling based on MRI revealed significant anomalies in IS patients compared to normal subjects. - Frequent aplasias located in the lateral canal were found in IS. - We also discovered a, never described, abnormal communication between lateral and posterior canal. - Lateral SCC is involved in trunk rotation and lateral deviation: these movements are frequently abnormal in IS. Supports: Fondation Yves Cotrel pour la recherche en pathologie rachidienne. Institut de France, Paris. SHFJ/CEA Orsay in the frame of the cooperation through IFR 49 INSERM/CNRS France.

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