Selective sweeps for recessive alleles and for other modes of dominance

Details Selective sweeps for recessive alleles and for other modes of dominance Selective sweeps for recessive alleles and for other modes of dominance

2010-05-30

arxiv.org/abs/1005.5536v2

Biology

Quantitative Biology

Populations and Evolution

Published in the Journal of Mathematical Biology. The final publication is available at http://www.springerlink.com

Scientific paper

A selective sweep describes the reduction of linked genetic variation due to strong positive selection. If s is the fitness advantage of a homozygote for the beneficial allele and h its dominance coefficient, it is usually assumed that h=1/2, i.e. the beneficial allele is co-dominant. We complement existing theory for selective sweeps by assuming that h is any value in [0,1]. We show that genetic diversity patters under selective sweeps with strength s and dominance 0

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