Biology – Quantitative Biology – Populations and Evolution
Scientific paper
2009-12-25
Biology
Quantitative Biology
Populations and Evolution
11 pages, 2 figures
Scientific paper
The quasispecies model describes processes related to the origin of life and viral evolutionary dynamics. We discuss how the error catastrophe that reflects the transition from localized to delocalized quasispecies population is affected by catalytic replication of different reaction orders. Specifically, we find that 2nd order mechanisms lead to 1st order discontinuous phase transitions in the viable population fraction, and conclude that the "higher" the interaction the "lower" the transition. We discuss potential implications for understanding the replication of highly mutating RNA viruses.
Ashkenasy Gonen
Tannenbaum Emmanuel
Wagner Nathaniel
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