Role of transport performance on neuron cell morphology

Biology – Quantitative Biology – Cell Behavior

Scientific paper

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9 pages with 3 figures, submitted to Neuroscience Letters

Scientific paper

10.1096/fj.06-5977com

The compartmental model is a basic tool for studying signal propagation in neurons, and, if the model parameters are adequately defined, it can also be of help in the study of electrical or fluid transport. Here we show that the input resistance, in different networks which simulate the passive properties of neurons, is the result of an interplay between the relevant conductances, morphology and size. These results suggest that neurons must grow in such a way that facilitates the current flow. We propose that power consumption is an important factor by which neurons attain their final morphological appearance.

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