Resonant imaging of carotenoid pigments in the human retina

Computer Science

Scientific paper

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Scientific paper

We have generated high spatial resolution images showing the distribution of carotenoid macular pigments in the human retina using Raman spectroscopy. A low level of macular pigments is associated with an increased risk of developing age-related macular degeneration, a leading cause of irreversible blindness. Using excised human eyecups and resonant excitation of the pigment molecules with narrow bandwidth blue light from a mercury arc lamp, we record Raman images originating from the carbon-carbon double bond stretch vibrations of lutein and zeaxanthin, the carotenoids comprising human macular pigments. Our Raman images reveal significant differences among subjects, both in regard to absolute levels as well as spatial distribution within the macula. Since the light levels used to obtain these images are well below established safety limits, this technique holds promise for developing a rapid screening diagnostic in large populations at risk for vision loss from age-related macular degeneration.

No associations

LandOfFree

Say what you really think

Search LandOfFree.com for scientists and scientific papers. Rate them and share your experience with other people.

Rating

Resonant imaging of carotenoid pigments in the human retina does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Resonant imaging of carotenoid pigments in the human retina, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Resonant imaging of carotenoid pigments in the human retina will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFWR-SCP-O-1201488

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.