Remarks on Feedforward Circuits, Adaptation, and Pulse Memory

Details Remarks on Feedforward Circuits, Adaptation, and Pulse Memory Remarks on Feedforward Circuits, Adaptation, and Pulse Memory

2008-12-03

arxiv.org/abs/0812.0622v2

Biology

Quantitative Biology

Quantitative Methods

Updates version 1; added many references, simulations, examples, and also more comments on approximate adaptation

Scientific paper

This note studies feedforward circuits as models for perfect adaptation to step signals in biological systems. A global convergence theorem is proved in a general framework, which includes examples from the literature as particular cases. A notable aspect of these circuits is that they do not adapt to pulse signals, because they display a memory phenomenon. Estimates are given of the magnitude of this effect.

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