Question 7: Modelling Minimal `Lipid-Peptide' Cells

Details Question 7: Modelling Minimal `Lipid-Peptide' Cells Question 7: Modelling Minimal `Lipid-Peptide' Cells

Oct 2007

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=2007oleb...37..433r&link_type=abstract

Origins of Life and Evolution of Biospheres, Volume 37, Issue 4-5, pp. 433-437

Mathematics

Logic

Minimal Lipid-Peptide Cells, Stochastic Kinetics (Gillespie Method), Proto-Metabolism, Osmotic Burst, Vesicle Reproduction

Scientific paper

This contribution is aimed to give support to ‘bottom-up’ approaches to the minimal or early cell research project. Even if, from this perspective, the most simple living cell still seems very far away, the analysis of less complex, infrabiological cellular systems (some of which could be relatively soon implemented in the lab) probably holds the key, or one of the fundamental keys, to the problem of origins of life. On these lines, we propose a simulation model to study the transition from proto-metabolic ‘lipid’ cells to ‘lipid-peptide’ cells, as a critical step in which self-reproducing vesicles could develop into more functionalized supramolecular systems

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