Question 6: Coevolution Theory of the Genetic Code: A Proven Theory

Details Question 6: Coevolution Theory of the Genetic Code: A Proven Theory Question 6: Coevolution Theory of the Genetic Code: A Proven Theory

Oct 2007

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=2007oleb...37..403w&link_type=abstract

Origins of Life and Evolution of Biospheres, Volume 37, Issue 4-5, pp. 403-408

Biology

Quantitative Biology

Genomics

1

Genetic Code, Coevolution Theory, Amino Acid Biosynthesis, Pretran Synthesis

Scientific paper

The coevolution theory proposes that primordial proteins consisted only of those amino acids readily obtainable from the prebiotic environment, representing about half the twenty encoded amino acids of today, and the missing amino acids entered the system as the code expanded along with pathways of amino acid biosynthesis. The isolation of genetic code mutants, and the antiquity of pretran synthesis revealed by the comparative genomics of tRNAs and aminoacyl-tRNA synthetases, have combined to provide a rigorous proof of the four fundamental tenets of the theory, thus solving the riddle of the structure of the universal genetic code.

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