Quasispecies Theory for Multiple-Peak Fitness Landscapes

Details Quasispecies Theory for Multiple-Peak Fitness Landscapes Quasispecies Theory for Multiple-Peak Fitness Landscapes

2006-08-15

arxiv.org/abs/q-bio/0608029v1

Phys. Rev. E 73 (2006) 041913

Biology

Quantitative Biology

Populations and Evolution

10 pages, 3 figures, 2 tables

Scientific paper

10.1103/PhysRevE.73.041913

We use a path integral representation to solve the Eigen and Crow-Kimura molecular evolution models for the case of multiple fitness peaks with arbitrary fitness and degradation functions. In the general case, we find that the solution to these molecular evolution models can be written as the optimum of a fitness function, with constraints enforced by Lagrange multipliers and with a term accounting for the entropy of the spreading population in sequence space. The results for the Eigen model are applied to consider virus or cancer proliferation under the control of drugs or the immune system.

Affiliated with

Also associated with

No associations

Rating

Quasispecies Theory for Multiple-Peak Fitness Landscapes does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Quasispecies Theory for Multiple-Peak Fitness Landscapes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Quasispecies Theory for Multiple-Peak Fitness Landscapes will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-99851