Quantifying Slow Evolutionary Dynamics in RNA Fitness Landscapes

Details Quantifying Slow Evolutionary Dynamics in RNA Fitness Landscapes Quantifying Slow Evolutionary Dynamics in RNA Fitness Landscapes

2009-11-28

arxiv.org/abs/0911.5366v1

Journal of Bioinformatics and Computational Biology, Vol. 8, No. 6, 2010

Biology

Quantitative Biology

Populations and Evolution

9 pages, 7 figures

Scientific paper

10.1142/S0219720010005075

We re-examine the evolutionary dynamics of RNA secondary structures under directional selection towards an optimum RNA structure. We find that the punctuated equilibria lead to a very slow approach to the optimum, following on average an inverse power of the evolutionary time. In addition, our study of the trajectories shows that the out-of-equilibrium effects due to the evolutionary process are very weak. In particular, the distribution of genotypes is close to that arising during equilibrium stabilizing selection. As a consequence, the evolutionary dynamics leave almost no measurable out-of-equilibrium trace, only the transition genotypes (close to the border between different periods of stasis) have atypical mutational properties.

Affiliated with

Also associated with

No associations

Rating

Quantifying Slow Evolutionary Dynamics in RNA Fitness Landscapes does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Quantifying Slow Evolutionary Dynamics in RNA Fitness Landscapes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Quantifying Slow Evolutionary Dynamics in RNA Fitness Landscapes will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-18331