Phase transition in the genome evolution favours non-random distribution of genes on chromosomes

Details Phase transition in the genome evolution favours non-random distribution of genes on chromosomes Phase transition in the genome evolution favours non-random distribution of genes on chromosomes

2009-01-08

arxiv.org/abs/0901.0990v1

Biology

Quantitative Biology

Genomics

13 pages, 7 figures, publication

Scientific paper

We have used the Monte Carlo based computer models to show that selection pressure could affect the distribution of recombination hotspots along the chromosome. Close to critical crossover rate, where genomes may switch between the Darwinian purifying selection or complementation of haplotypes, the distribution of recombination events and the force of selection exerted on genes affect the structure of chromosomes. The order of expression of gene s and their location on chromosome may decide about the extinction or survival of competing populations.

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