Optothermal skin pigment spectral depth profiling using an OPO laser

Details Optothermal skin pigment spectral depth profiling using an OPO laser Optothermal skin pigment spectral depth profiling using an OPO laser

Jun 1999

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=1999spie.3601..348x&link_type=abstract

Proc. SPIE Vol. 3601, p. 348-354, Laser-Tissue Interaction X: Photochemical, Photothermal, and Photomechanical, Steven L. Jacque

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Scientific paper

This paper presents the results of a research program to quantify the factors that determine the visual appearance of human skin. We use in-vivo opto-thermal transient emission radiometry (OTTER) with a tunable OPO laser (400 - 590 nm) to measure spectrally resolved pigment depth profiles. Radiation in this wavelength range is only weakly absorbed by stratum corneum and epidermis, but strongly absorbed by sub-surface pigments, mainly melanin and haemoglobin. These produce characteristic delayed thermal wave (DTW) signals, detected using a high speed Mercury Cadmium Telluride detector sensitive in the wavelength range 6 - 13 microns. The measured intensity-time profiles yield the desired concentration depth profiles through either model-based non-linear least-squares analysis or model-independent inverse analysis. Results on melanin and haemoglobin distributions within normal, tape stripped and wash-damaged skin are presented.

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