Non-Maxwellian velocity distribution and anomalous diffusion of {\it in vitro} kidney cells

Details Non-Maxwellian velocity distribution and anomalous diffusion of {\it in vitro} kidney cells Non-Maxwellian velocity distribution and anomalous diffusion of {\it in vitro} kidney cells

2005-03-07

arxiv.org/abs/q-bio/0503013v1

Biology

Quantitative Biology

Cell Behavior

19 pages 5 figs

Scientific paper

This manuscript uses a statistical mechanical approach to study the effect of the adhesion, through MOCA protein, on cell locomotion. The MOCA protein regulates cell-cell adhesion, and we explore its potential role in the cell movement. We present a series of statistical descriptions of the motion in order to characterize the cell movement, and found that MOCA affects the statistical scenario of cell locomotion. In particular, we observe that MOCA enhances the tendency of joint motion, inhibits super-diffusion, and decreases overall cell motion. These facts are compatible with the hypothesis that the cells move faster in a less cohesive environment. Furthermore, we observe that velocity distribution tails are longer than those predicted by Maxwell-Boltzmann in all cases studied here, indicating that cell movement is more complex than that of a liquid.

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