New method for the study of psychotropic drug effects under simulated clinical conditions

Details New method for the study of psychotropic drug effects under simulated clinical conditions New method for the study of psychotropic drug effects under simulated clinical conditions

2007-07-25

arxiv.org/abs/0707.3671v2

Biology

Quantitative Biology

Other Quantitative Biology

15 pages, 9 figures, 5 tables

Scientific paper

The sensory contact model allows forming different psychopathological states (anxious depression, catalepsy, social withdrawal, pathological aggression, hypersensitivity, cognition disturbances, anhedonia, alcoholism etc.) produced by repeated agonistic interactions in male mice and investigating the therapeutic and preventive properties of any drug as well as its efficiency under simulated clinical conditions. This approach can be useful for a better understanding of the drugs' action in different stages of disease development in individuals. It is suggested that this pharmacological approach may be applied for the screening of different novel psychotropic drugs.

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