Modelling of the prebiotic synthesis of oligopeptides: silicate catalysts help to overcome the critical stage

Details Modelling of the prebiotic synthesis of oligopeptides: silicate catalysts help to overcome the critical stage Modelling of the prebiotic synthesis of oligopeptides: silicate catalysts help to overcome the critical stage

Aug 1997

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=1997oleb...27..325z&link_type=abstract

Origins of Life and Evolution of the Biosphere, v. 27, Issue 4, p. 325-337 (1997).

Other

10

Scientific paper

On the basis of experimental studies of the initial stages of glycine oligomerization in aqueous suspension of zeolite and kaolinite catalysts, a model is suggested for the prebiotic synthesis of oligopeptides from α-amino acids. The formation of linear dipeptides by hydrolysis of one amide bond in the cyclic piperazinedione intermediate (formed from glycine spontaneously) is found to be the critical stage of the reaction. This stage is base catalyzed and its rate increases when pH of the medium goes up. The linear glycyl-glycine yield rises under effect of hydroxyl anions generated from different sources including insoluble silicates and soluble sodium bicarbonate. During prebiotic evolution silicates capable of cation-exchange can serve as local sources of the hydroxyl anions which dramatically accelerate formation of linear dipeptides from cyclic ones. Oligopeptides of higher molecular weight are then easily formed from the linear dipeptides at neutral pH, even in the absence of catalysts or sources of energy (e.g. such as light). The described catalytic synthesis could occur in the proximity of submarine hydrothermal vents.

Affiliated with

Also associated with

No associations

Rating

Modelling of the prebiotic synthesis of oligopeptides: silicate catalysts help to overcome the critical stage does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Modelling of the prebiotic synthesis of oligopeptides: silicate catalysts help to overcome the critical stage, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Modelling of the prebiotic synthesis of oligopeptides: silicate catalysts help to overcome the critical stage will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-807365