Modelling Immunological Memory

Details Modelling Immunological Memory Modelling Immunological Memory

2010-04-21

arxiv.org/abs/1004.3932v1

In Silico Immunology, 83-108, 2006

Computer Science

Artificial Intelligence

26 pages, In Silico Immunology

Scientific paper

Accurate immunological models offer the possibility of performing highthroughput experiments in silico that can predict, or at least suggest, in vivo phenomena. In this chapter, we compare various models of immunological memory. We first validate an experimental immunological simulator, developed by the authors, by simulating several theories of immunological memory with known results. We then use the same system to evaluate the predicted effects of a theory of immunological memory. The resulting model has not been explored before in artificial immune systems research, and we compare the simulated in silico output with in vivo measurements. Although the theory appears valid, we suggest that there are a common set of reasons why immunological memory models are a useful support tool; not conclusive in themselves.

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