Computer Science – Computational Engineering – Finance – and Science
Scientific paper
2009-11-26
EPTCS 11, 2009, pp. 51-69
Computer Science
Computational Engineering, Finance, and Science
Scientific paper
10.4204/EPTCS.11.4
Understanding the behaviour of biological systems requires a complex setting of in vitro and in vivo experiments, which attracts high costs in terms of time and resources. The use of mathematical models allows researchers to perform computerised simulations of biological systems, which are called in silico experiments, to attain important insights and predictions about the system behaviour with a considerably lower cost. Computer visualisation is an important part of this approach, since it provides a realistic representation of the system behaviour. We define a formal methodology to model biological systems using different levels of representation: a purely formal representation, which we call molecular level, models the biochemical dynamics of the system; visualisation-oriented representations, which we call visual levels, provide views of the biological system at a higher level of organisation and are equipped with the necessary spatial information to generate the appropriate visualisation. We choose Spatial CLS, a formal language belonging to the class of Calculi of Looping Sequences, as the formalism for modelling all representation levels. We illustrate our approach using the budding yeast cell cycle as a case study.
Basuki Thomas Anung
Carvalho Rafael V.
Cerone Antonio
No associations
LandOfFree
Modelling Cell Cycle using Different Levels of Representation does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.
If you have personal experience with Modelling Cell Cycle using Different Levels of Representation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Modelling Cell Cycle using Different Levels of Representation will most certainly appreciate the feedback.
Profile ID: LFWR-SCP-O-116125