Computer Science
Scientific paper
Aug 2011
adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=2011oleb...41..347r&link_type=abstract
Origins of Life and Evolution of Biospheres, Volume 41, Issue 4, pp.347-356
Computer Science
Fes Clusters, Fes Protein Folds, Pyrite-Dependent Primordial Autotrophy, Aminoacyl-Trna Synthetases, Reverse Krebs Cycle
Scientific paper
We critically examine the proposal by Wächtershäuser (Prokaryotes 1:275-283, 2006a, Philos Trans R Soc Lond B Biol Sci 361: 787-1808, 2006b) that putative transition metal binding sites in protein components of the translation machinery of hyperthermophiles provide evidence of a direct relationship with the FeS clusters of pyrite and thus indicate an autotrophic origin of life in volcanic environments. Analysis of completely sequenced cellular genomes of Bacteria, Archaea and Eucarya does not support the suggestion by Wächtershäuser (Prokaryotes 1:275-283, 2006a, Philos Trans R Soc Lond B Biol Sci 361: 787-1808, 2006b) that aminoacyl-tRNA synthetases and ribosomal proteins bear sequence signatures typical of strong covalent metal bonding whose absence in mesophilic species reveals a process of adaptation towards less extreme environments.
Bada Jeffrey L.
Becerra Arturo
Lazcano Antonio
Pereto Juli
Rivas Mario
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