Mechanochemical coupling of kinesin studied with the neck linker swing model

Details Mechanochemical coupling of kinesin studied with the neck linker swing model Mechanochemical coupling of kinesin studied with the neck linker swing model

2006-01-24

arxiv.org/abs/q-bio/0601040v1

Biology

Quantitative Biology

Other Quantitative Biology

5pages

Scientific paper

We have proposed the neck linker swing model to investigate the mechanism of mechanochemical coupling of kinesin. The Michaelis-Menten-like curve for velocity vs ATP concentration at different loads has been obtained, which is in agreement with experiments. We have predicted that Michaelis constant doesn't increase monotonically and an elastic instability will happen with increasing of applied force.

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