Is the general time-reversible model bad for molecular phylogenetics?

Details Is the general time-reversible model bad for molecular phylogenetics? Is the general time-reversible model bad for molecular phylogenetics?

2011-11-03

arxiv.org/abs/1111.0723v1

Biology

Quantitative Biology

Populations and Evolution

10 pages, 2 figures

Scientific paper

10.1093/sysbio/sys042

The general time reversible model (GTR) is presently the most popular model
used in phylogentic studies. However, GTR has an undesirable mathematical
property that is potentially of significant concern. It is the purpose of this
article to give examples that demonstrate why this deficit may pose a problem
for phylogenetic analysis and interpretation.

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