Computer Science – Artificial Intelligence
Scientific paper
2010-07-30
TPLP 2010, 10 (4-6) 449-464
Computer Science
Artificial Intelligence
Scientific paper
A Hidden Markov Model (HMM) is a common statistical model which is widely used for analysis of biological sequence data and other sequential phenomena. In the present paper we show how HMMs can be extended with side-constraints and present constraint solving techniques for efficient inference. Defining HMMs with side-constraints in Constraint Logic Programming have advantages in terms of more compact expression and pruning opportunities during inference. We present a PRISM-based framework for extending HMMs with side-constraints and show how well-known constraints such as cardinality and all different are integrated. We experimentally validate our approach on the biologically motivated problem of global pairwise alignment.
Christiansen Henning
Have Christian Theil
Lassen Ole Torp
Petit Matthieu
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