Hypobaric Hypoxia: Effects on Early Development of Tryptophan Oxygenase in Neonatal Rats

Details Hypobaric Hypoxia: Effects on Early Development of Tryptophan Oxygenase in Neonatal Rats Hypobaric Hypoxia: Effects on Early Development of Tryptophan Oxygenase in Neonatal Rats

Dec 1969

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=1969sci...166.1412f&link_type=abstract

Science, Volume 166, Issue 3911, pp. 1412-1413

Computer Science

Scientific paper

Despite a reduction in liver and body weights of neonatal rats born and reared at a simulated altitude of 5790 meters (oxygen pressure, 76.36 millimeters of mercury), the hepatic enzyme tryptophan oxygenase develops prematurely in these stressed animals as compared to controls reared at sea level. Also, the specific activities remain distinctly elevated through the first 9 days of age; thus, the competence for premature synthesis of tryptophan oxygenase is confirmed in neonatal rats.

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