Mathematics – Dynamical Systems
Scientific paper
2006-10-23
Mathematics
Dynamical Systems
18 pages, 12 figures, the paper was presented at "Conference Francophone sur la Modelisation Mathematique en Biologie et en Me
Scientific paper
The aim of this paper is to study the steady states of the mathematical models with delay kernels which describe pathogen-immune dynamics of many kinds of infectious diseases. In the study of mathematical models of infectious diseases it is important to predict whether the infection disappears or the pathogens persist. The delay kernel is described by the memory function that reflects the influence of the past density of pathogen in the blood. By using the coefficient of kernel k, as a bifurcation parameter, the models are found to undergo a sequence of Hopf bifurcation. The direction and the stability criteria of bifurcation periodic solutions are obtained by applying the normal form theory and the center manifold theorems. Some numerical simulation examples for justifying the theoretical results are also given.
Buliga L.
Ceausu A. T.
Horhat Raul Florin
Neamtu Mihaela
Opris Dumitru
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