Astronomy and Astrophysics – Astronomy
Scientific paper
Oct 1994
adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=1994adspr..14..443s&link_type=abstract
Advances in Space Research, Volume 14, Issue 10, p. 443-451.
Astronomy and Astrophysics
Astronomy
Scientific paper
Application of the degeneration sensitive, cupric-silver staining method to brain sections of male Sprague-Dawley rats irradiated 4 days before sacrifice with 155 Mev protons, 2-8 Gy at 1 Gy/min (N=6) or 22-101Gy at 20 Gy/min (N=16) or with 18.6 Mev electrons, 32-67 Gy at 20 Gy/min (N=20), doses which elicit behavioral changes (accelerod or conditioned taste aversion), resulted in a display of degeneration of astrocyte-like cell profiles which were not uniformly distributed. Plots of `degeneration scores' (counts of profiles in 29 areas) vs. dose for the proton and electron irradiations displayed a linear dose response for protons in the range of 2-8 Gy. In the 20-100 Gy range, for both electrons and protons the points were distributed in a broad band suggesting a saturation curve. The dose range in which these astrocyte-like profiles becomes maximal corresponds well with the dose range for the X-ray eradication of a subtype of astrocytes, `beta astrocytes`.
Bogo V.
Mickley G. A.
Switzer Robert C.
No associations
LandOfFree
Histologic effects of high energy electron and proton irradiation of rat brain detected with a silver-degeneration stain does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.
If you have personal experience with Histologic effects of high energy electron and proton irradiation of rat brain detected with a silver-degeneration stain, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Histologic effects of high energy electron and proton irradiation of rat brain detected with a silver-degeneration stain will most certainly appreciate the feedback.
Profile ID: LFWR-SCP-O-1069117