Gravity sensing in the retinal spreading depression, an in-vitro model for the central nervous system (CNS)

Biology

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Microgravity, Biology

Scientific paper

The retinal spreading depression (SD) was used to study the effects of altered gravity on the central nervous system (CNS). The SD is an excitation depression wave and an example of self-organization and pattern formation in neuronal tissue being an excitable media. Until now it is not much known about how changes in gravity effect the central nervous system. Here we present the results of SD experiments on a sounding rocket mission (TEXUS 41) and the comparison to earlier SD experiments on parabolic flights (2nd and 3rd DLR Parabolic flight campaign) and centrifuge experiments in our lab. The results of these experimetns show that the properties of the SD and therefore the CNS in its properties as an excitable medium reacts very sensitive to changes in gravity.

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