Flow correlated percolation during vascular network formation in tumors

Details Flow correlated percolation during vascular network formation in tumors Flow correlated percolation during vascular network formation in tumors

2005-07-28

arxiv.org/abs/q-bio/0507043v1

Phys. Rev. Lett. 96, 058104 (2006)

Biology

Quantitative Biology

Tissues and Organs

4 pages, 3 figures (higher resolution at http://www.uni-saarland.de/fak7/rieger/HOMEPAGE/flow.eps)

Scientific paper

10.1103/PhysRevLett.96.058104

A theoretical model based on the molecular interactions between a growing tumor and a dynamically evolving blood vessel network describes the transformation of the regular vasculature in normal tissues into a highly inhomogeneous tumor specific capillary network. The emerging morphology, characterized by the compartmentalization of the tumor into several regions differing in vessel density, diameter and necrosis, is in accordance with experimental data for human melanoma. Vessel collapse due to a combination of severely reduced blood flow and solid stress exerted by the tumor, leads to a correlated percolation process that is driven towards criticality by the mechanism of hydrodynamic vessel stabilization.

Affiliated with

Also associated with

No associations

Rating

Flow correlated percolation during vascular network formation in tumors does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Flow correlated percolation during vascular network formation in tumors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Flow correlated percolation during vascular network formation in tumors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-46915