Experimental Researches of Cutaneous Melanoma Immunotherapy by Antitumor Cell-Whole GM-CSF-Producing Vaccines

Details Experimental Researches of Cutaneous Melanoma Immunotherapy by Antitumor Cell-Whole GM-CSF-Producing Vaccines Experimental Researches of Cutaneous Melanoma Immunotherapy by Antitumor Cell-Whole GM-CSF-Producing Vaccines

2011-10-12

arxiv.org/abs/1110.2966v1

Russian Journal of Biotherapy. 3/2010.-#3- P.47-50

Biology

Quantitative Biology

Other Quantitative Biology

8 pages, 4 figures; ISSN 1726-9784. Russian Journal of Biotherapy. /2010.-#3- P.47-50

Scientific paper

Various approaches to increase efficiency of antitumor therapy by a combination of vaccinotherapy, chemotherapy and surgical excision of primary tumor nodes, and also the comparative analyses of therapeutic and preventive application of antitumoral vaccines were carried out in melanoma experimental model. It was postulated that preventive vaccination is able to prevent tumor incidence by 70 %. The combination of vaccinotherapy and surgical treatment of melanoma increases antimetastatic activity of vaccination by 43 %. We conclude the combined therapy would lead to more effective antitumor response.

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