Experimental Evidence Leading to an Alternative Explanation of Why D-tyrosine Sometimes Crystallizes Faster than Its L-Enantiomer

Mathematics – Logic

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Tyrosine, Diastereomeric Effect, Airborne, Nonracemic, Chiral, Fungal Spore, Parity Violation Energy Difference

Scientific paper

On the occasions when D-tyrosine is observed to crystallize faster than its L-enantiomer, it is the result of a diastereomeric interaction between an airborne, non-racemic, chiral influence—probably a fungal spore—and the tyrosine enantiomers, enhancing the degree of crystal nucleation of D-tyrosine over L-tyrosine. This explanation, supported by experimental evidence, is presented as a more plausible alternative to the Shinitzky Deamer hypothesis (Shinitzky et al., Progress in biological chirality, Elsevier, Amsterdam, pp. 329 337, 2004; Deamer et al., Chirality, 19:751 763, 2007) which relies on the parity violation energy difference between enantiomers, a femtojoule to picojoule per mole theoretical energy range.

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