Estimation of nonlinear models with Berkson measurement errors

Mathematics – Statistics Theory

Scientific paper

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Published at http://dx.doi.org/10.1214/009053604000000670 in the Annals of Statistics (http://www.imstat.org/aos/) by the Inst

Scientific paper

10.1214/009053604000000670

This paper is concerned with general nonlinear regression models where the predictor variables are subject to Berkson-type measurement errors. The measurement errors are assumed to have a general parametric distribution, which is not necessarily normal. In addition, the distribution of the random error in the regression equation is nonparametric. A minimum distance estimator is proposed, which is based on the first two conditional moments of the response variable given the observed predictor variables. To overcome the possible computational difficulty of minimizing an objective function which involves multiple integrals, a simulation-based estimator is constructed. Consistency and asymptotic normality for both estimators are derived under fairly general regularity conditions.

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