Mathematics – Statistics Theory
Scientific paper
2005-08-15
Biometrika 2007, Vol. 94, No. 1, 199-216
Mathematics
Statistics Theory
25 pages
Scientific paper
10.1093/biomet/asm007
We consider estimation of the covariance matrix of a multivariate random vector under the constraint that certain covariances are zero. We first present an algorithm, which we call Iterative Conditional Fitting, for computing the maximum likelihood estimator of the constrained covariance matrix, under the assumption of multivariate normality. In contrast to previous approaches, this algorithm has guaranteed convergence properties. Dropping the assumption of multivariate normality, we show how to estimate the covariance matrix in an empirical likelihood approach. These approaches are then compared via simulation and on an example of gene expression.
Chaudhuri Sanjay
Drton Mathias
Richardson Thomas S.
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