Dynamics of conduction blocks in a model of paced cardiac tissue

Details Dynamics of conduction blocks in a model of paced cardiac tissue Dynamics of conduction blocks in a model of paced cardiac tissue

2005-04-06

arxiv.org/abs/q-bio/0504009v1

Biology

Quantitative Biology

Tissues and Organs

8 pages 6 figures

Scientific paper

10.1103/PhysRevE.71.051911

We study numerically the dynamics of conduction blocks using a detailed electrophysiological model. We find that this dynamics depends critically on the size of the paced region. Small pacing regions lead to stationary conduction blocks while larger pacing regions can lead to conduction blocks that travel periodically towards the pacing region. We show that this size-dependence dynamics can lead to a novel arrhythmogenic mechanism. Furthermore, we show that the essential phenomena can be captured in a much simpler coupled-map model.

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