Biology – Quantitative Biology – Subcellular Processes
Scientific paper
2006-03-30
Biology
Quantitative Biology
Subcellular Processes
4 pages, 3 figures
Scientific paper
We analyze the role of the force-dependent kinetics of motor proteins in the stability of antiparallel arrays of polar filaments, such as those in the mitotic spindle. We determine the possible stable structures and show that there exists an instability associated to the collective behavior of motors that leads to the collapse of the spindle. Our analysis provides a general framework to understand several experimental observations in eukaryotic cell division.
Campas Otger
Casademunt Jaume
Pagonabarraga Ignacio
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