Dynamic Stability and Thermodynamic Characterization in an Enzymatic Reaction at the Single Molecule Level

Details Dynamic Stability and Thermodynamic Characterization in an Enzymatic Reaction at the Single Molecule Level Dynamic Stability and Thermodynamic Characterization in an Enzymatic Reaction at the Single Molecule Level

2010-11-24

arxiv.org/abs/1011.5431v4

Biology

Quantitative Biology

Subcellular Processes

In Press in Physica A

Scientific paper

In this work we study, at the single molecular level, the thermodynamic and dynamic characteristics of an enzymatic reaction comprising a rate limiting step. We investigate how the stability of the enzyme-state stationary probability distribution, the reaction velocity, and its efficiency of energy conversion depend on the system parameters. We employ in this study a recently introduced formalism for performing a multiscale thermodynamic analysis in continuous-time discrete-state stochastic systems.

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