Biology – Quantitative Biology – Neurons and Cognition
Scientific paper
2007-11-02
Biology
Quantitative Biology
Neurons and Cognition
Scientific paper
Based upon the membrane currents generated by an action potential in a biologically realistic model of a pyramidal, hippocampal cell within rat CA1, we perform a moment expansion of the extracellular field potential. We decompose the potential into both inverse and classical moments and show that this method is a rapid and efficient way to calculate the extracellular field both near and far from the cell body. The action potential gives rise to a large quadrupole moment that contributes to the extracellular field up to distances of almost 1 cm. This method will serve as a starting point in connecting the microscopic generation of electric fields at the level of neurons to macroscopic observables such as the local field potential.
Koch Christof
Milstein J. N.
No associations
LandOfFree
Dynamic Moment Analysis of the Extracellular Electric Field of a Biologically Realistic Spiking Neuron does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.
If you have personal experience with Dynamic Moment Analysis of the Extracellular Electric Field of a Biologically Realistic Spiking Neuron, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Dynamic Moment Analysis of the Extracellular Electric Field of a Biologically Realistic Spiking Neuron will most certainly appreciate the feedback.
Profile ID: LFWR-SCP-O-507620