Detection of Aneuploidy with Digital PCR

Details Detection of Aneuploidy with Digital PCR Detection of Aneuploidy with Digital PCR

2007-05-08

arxiv.org/abs/0705.1030v1

Biology

Quantitative Biology

Quantitative Methods

Scientific paper

The widespread use of genetic testing in high risk pregnancies has created strong interest in rapid and accurate molecular diagnostics for common chromosomal aneuploidies. We show here that digital polymerase chain reaction (dPCR) can be used for accurate measurement of trisomy 21 (Down's Syndrome), the most common human aneuploidy. dPCR is generally applicable to any aneuploidy, does not depend on allelic distribution or gender, and is able to detect signals in the presence of mosaics or contaminating maternal DNA.

Affiliated with

Also associated with

No associations

Rating

Detection of Aneuploidy with Digital PCR does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Detection of Aneuploidy with Digital PCR, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Detection of Aneuploidy with Digital PCR will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-153245