Design of a dynamic model of genes with multiple autonomous regulatory modules by evolution in silico

Biology – Quantitative Biology – Quantitative Methods

Scientific paper

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24 pages

Scientific paper

New approach to design a dynamic model of genes with multiple autonomous regulatory modules by evolution in silico is proposed. The approach is based on Genetic Algorithms, enforced by new crossover operators, especially worked out for these purposes. The approach exploits the subbasin-portal architecture of the fitness functions suitable for this kind of evolutionary modeling. The effectiveness of the approach is demonstrated on a series of benchmark tests.

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