Decomposition of neuronal assembly activity via empirical de-Poissonization

Mathematics – Statistics Theory

Scientific paper

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Published in at http://dx.doi.org/10.1214/07-EJS095 the Electronic Journal of Statistics (http://www.i-journals.org/ejs/) by t

Scientific paper

10.1214/07-EJS095

Consider a compound Poisson process with jump measure $\nu$ supported by finitely many positive integers. We propose a method for estimating $\nu$ from a single, equidistantly sampled trajectory and develop associated statistical procedures. The problem is motivated by the question whether nerve cells in the brain exhibit higher-order interactions in their firing patterns. According to the neuronal assembly hypothesis (Hebb [13]), synchronization of action potentials across neurons of different groups is considered a signature of assembly activity, but it was found notoriously difficult to demonstrate it in recordings of neuronal activity. Our approach based on a compound Poisson model allows to detect the presence of joint spike events of any order using only population spike count samples, thus bypassing both the ``curse of dimensionality'' and the need to isolate single-neuron spike trains in population signals.

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