D-Amino Acids in Living Higher Organisms

Details D-Amino Acids in Living Higher Organisms D-Amino Acids in Living Higher Organisms

Apr 2002

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=2002oleb...32..103f&link_type=abstract

Origins of Life and Evolution of the Biosphere, v. 32, Issue 2, p. 103-127 (2002).

Mathematics

Logic

3

Aging, D-Amino Acid, Development, Homochirality, Isomerization, Neuropeptides, Opioid Peptides, Origin Of Life, Racemization

Scientific paper

The homochirality of biological amino acids (L-amino acids) and of the RNA/DNA backbone (D-ribose) might have become established before the origin of life. It has been considered that D-amino acids and L-sugars were eliminated on the primitive Earth. Therefore, the presence and function of D-amino acids in living organisms have not been studied except for D-amino acids in the cell walls of microorganisms. However, D-amino acids were recently found in various living higher organisms in the form of free amino acids, peptides, and proteins. Free D-aspartate and D-serine are present and may have important physiological functions in mammals. D-amino acids in peptides are well known as opioid peptides and neuropeptides. In protein, D-aspartate residues increase during aging. This review deals with recent advances in the study of D-amino acids in higher organisms.

Affiliated with

Also associated with

No associations

Rating

D-Amino Acids in Living Higher Organisms does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with D-Amino Acids in Living Higher Organisms, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and D-Amino Acids in Living Higher Organisms will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-849657