Computation of amplification for systems arising from cellular signaling pathways

Details Computation of amplification for systems arising from cellular signaling pathways Computation of amplification for systems arising from cellular signaling pathways

2004-08-16

arxiv.org/abs/q-bio/0408012v1

Biology

Quantitative Biology

Quantitative Methods

See http://www.math.rutgers.edu/~sontag/ for related papers

Scientific paper

A commonly employed measure of the signal amplification properties of an input/output system is its induced L2 norm, sometimes also known as "H infinity" gain. In general, however, it is extremely difficult to compute the numerical value for this norm, or even to check that it is finite, unless the system being studied is linear. This paper describes a class of systems for which it is possible to reduce this computation to that of finding the norm of an associated linear system. In contrast to linearization approaches, a precise value, not an estimate, is obtained for the full nonlinear model. The class of systems that we study arose from the modeling of certain biological intracellular signaling cascades, but the results should be of wider applicability.

Affiliated with

Also associated with

No associations

Rating

Computation of amplification for systems arising from cellular signaling pathways does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Computation of amplification for systems arising from cellular signaling pathways, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Computation of amplification for systems arising from cellular signaling pathways will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-580227