Complex Network Approach to Human Promoter Sequences

Biology – Quantitative Biology – Genomics

Scientific paper

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12 pages, 8 figures

Scientific paper

Based upon the correlation matrix of the human promoter sequences, a complex network is constructed to capture the principal relationships between these promoters. It is a complex network has the properties of the right-skewed degree distribution and the clustering simultaneously, i.e., a hierarchical structure. An eigenvector centrality (EC) based method is used to reconstruct this hierarchical structure.

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