Colloidal particle motion as a diagnostic of DNA conformational transitions

Details Colloidal particle motion as a diagnostic of DNA conformational transitions Colloidal particle motion as a diagnostic of DNA conformational transitions

2007-10-04

arxiv.org/abs/0710.1048v1

Biology

Quantitative Biology

Quantitative Methods

19pp. Accepted for publication in Curr Op Colloid Interf Science

Scientific paper

Tethered particle motion is an experimental technique to monitor
conformational changes in single molecules of DNA in real time, by observing
the position fluctuations of a micrometer-size particle attached to the DNA.
This article reviews some recent work on theoretical problems inherent in the
interpretation of TPM experiments, both in equilibrium and dynamical aspects.

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