Collective Langevin Dynamics of Flexible Cytoskeletal Fibers

Details Collective Langevin Dynamics of Flexible Cytoskeletal Fibers Collective Langevin Dynamics of Flexible Cytoskeletal Fibers

2009-03-30

arxiv.org/abs/0903.5178v1

Francois Nedelec et al 2007 New J. Phys. 9 427

Biology

Quantitative Biology

Cell Behavior

27 pages, 10 figures

Scientific paper

10.1088/1367-2630/9/11/427

We develop a numerical method to simulate mechanical objects in a viscous medium at a scale where inertia is negligible. Fibers, spheres and other voluminous objects are represented with points. Different types of connections are used to link the points together and in this way create composite mechanical structures. The motion of such structures in a Brownian environment is described by a first-order multivariate Langevin equation. We propose a computationally efficient method to integrate the equation, and illustrate the applicability of the method to cytoskeletal modeling with several examples.

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